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CDKN1B Polyclonal Antibody
Výrobce: Bioss Katalogové č.: bs-0742R Aplikace: Western Blot, Imunofluorescence, Imunohistochemie, Průtoková cytometrie, ELISA, ELISPOT Reaktivita: Human, Mouse, Rat, Chicken Původ: Rabbit Klonalita: Polyclonal Podtřída: IgG Status: RUO Dodatečné informace: Produkt na webu výrobce Popis:KIP1; MEN4; CDKN4; MEN1B; P27KIP1; Cyclin-dependent kinase inhibitor 1B; Cyclin-dependent kinase inhibitor p27; CDKN1B
Important regulator of cell cycle progression. Involved in G1 arrest. Potent inhibitor of cyclin E and cyclin ACDK2 complexes. Forms a complex with cyclin type DCDK4 complexes and is involved in the assembly, stability, and modulation of CCND1CDK4 complex activation. Acts either as an inhibitor or an activator of cyclin type DCDK4 complexes depending on its phosphorylation state and/or stoichometry.