ERAB Polyclonal Antibody
Výrobce: Bioss Katalogové č.: bs-0021M Aplikace: Imunofluorescence, Imunohistochemie, ELISA, ELISPOT Reaktivita: Ostatní Původ: Mouse Klonalita: Polyclonal Podtřída: IgG Status: RUO Dodatečné informace: Produkt na webu výrobce Popis:HSD17B10; Mitochondrial L3 Hydroxyacyl CoA Dehydrogenase; 17 beta hydroxysteroid dehydrogenase 10; 17 beta hydroxysteroid dehydrogenase type 10; 17b HSD10; 3 hydroxy 2 methylbutyryl CoA dehydrogenase; 3 hydroxyacyl CoA dehydrogenase type 2;
This gene encodes 3hydroxyacylCoA dehydrogenase type II, a member of the shortchain dehydrogenase/reductase superfamily. The gene product is a mitochondrial protein that catalyzes the oxidation of a wide variety of fatty acids, alcohols, and steroids. The protein has been implicated in the development of Alzheimer's disease, and mutations in the gene are the cause of 2methyl3hydroxybutyrylCoA dehydrogenase deficiency (MHBD). Several alternatively spliced transcript variants have been identified, but the fulllength nature of only two transcript variants has been determined. [provided by RefSeq, Jul 2008].