MATH2/NEUROD6 Polyclonal Antibody, Biotin Conjugated

Atoh 2; Atoh2; Atonal homolog 2; Atonal protein homolog 2; Atonal protein homolog2; bHLH a2 antibodybHLHa 2; bHLHa2; Class A basic helix-loop-helix protein 2; Helix loop helix protein mATH 2; Helix loop helix protein mATH2; MATH 2; Math2; NDF 6; NDF6; NDF6_HUMAN; Neuro D6; NeuroD6; Neurogenic dferentiation 6; Neurogenic dferentiation factor 6; Nex 1 antibodyNex 1m; Nex; Nex1; Nex1 m; Nex1m; Protein atonal homolog 2; Protein atonal homolog2.

The Drosophila atonal gene produces a protein with basic helix loop helix (bHLH) domains that plays an essential role in the development of the Drosophila nervous system. Mammalian atonal homolog 2 (MATH2) is a helixloophelix (HLH) transcription factor that is structurally homologous to the product of Drosophila atonal gene. MATH2 is a 337 amino acid protein with an atonalrelated basic HLH domain. In mice, expression of MATH2 takes place by embryonic day 11.5 and initially localizes to the wall of brain vesicles and in the spinal cord. It is expressed in the cortical plate and the mantle layer in the developing central nervous system, and is limited to the nervous system in adults. Adult mouse cerebrums produce a high level of MATH2 RNA with lower levels in other neuronal tissues. Research studies suggest that MATH2 may function as a transacting factor involved in the development and maintenance of the mammalian nervous system.