Unconjugated Mouse anti-Mouse Mouse Irgm1 (3T5) Monoclonal Antibody [IgM]

Ifi1; Irgm; Iigp3; Iipg3; Ifggd3; LRG-47; Immunity-related GTPase family M protein 1; Interferon-inducible GTPase 3; Interferon-inducible protein 1; LPS-stimulated RAW 264.7 macrophage protein 47; Irgm1

Putative GTPase which is required for IFNG-mediated clearance of acute protozoan and bacterial infections. Functions in innate immune response probably through regulation of autophagy. May regulate proinflammatory cytokine production and prevent endotoxemia upon infection. Required for macrophage motility and possibly also for adhesion.