Orexin B Polyclonal Antibody

OX; PPOX; NRCLP1; Orexin; Hypocretin; Hcrt; PPORX

Neuropeptides that play a significant role in the regulation of food intake and sleepwakefulness, possibly by coordinating the complex behavioral and physiologic responses of these complementary homeostatic functions. A broader role in the homeostatic regulation of energy metabolism, autonomic function, hormonal balance and the regulation of body fluids, is also suggested. OrexinA binds to both OX1R and OX2R with a high affinity, whereas orexinB binds only to OX2R with a similar high affinity.