ALEXA FLUOR 594 Rabbit anti-Human, Rat Histone H3 (Ser11) Polyclonal Antibody, ALEXA FLUOR 594 Conjugated [IgG]

H3t; H3.4; H3/g; H3FT; Histone H3.1t; H3/t; HIST3H3

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.